Li, Zhe,Guz, Nathan,Shao, Yiyang,Cocuz, Julieana,Frieser, Markus,Yiannikouros, George Petros,Liao, Liang
申请号：
AU2017261730
公开号：
AU2017261730A1
申请日:
2017.05.11
申请国别(地区):
AU
年份:
2018
代理人:
摘要：
Disclosed herein are processes for synthesizing 2-hydroxy-6-((2-(1-isopropyl-1H- pyrazol-5-yl)-pyridin-3-yl)methoxy)benzaldehyde (also referred to herein as Compound (I)) and intermediates used in such processes. Compound (I) binds to hemoglobin and increases it oxygen affinity and hence can be useful for the treatment of diseases such as sickle cell disease.
