SHELBY, NANCY JANE,SCOTT, STEVEN M.,LUCHSINGER, BENJAMIN P.,JUDA, GREGORY A.,KIRKER, KELLY R.,HERNANDEZ, JESUS,HOLMES, DARREL L.
申请号:
EP08768038
公开号:
EP2166988A4
申请日:
2008.06.02
申请国别(地区):
EP
年份:
2012
代理人:
摘要:
A demineralized bone matrix is produced by a process in which a bone body is placed in a first processing solution comprising an acid to demineralize the bone body. The bone body is periodically removed from the first solution at specific time intervals to perform at least one test, such as a compression test, on a mechanical property of the bone body. When the test yields a desired result, the bone body is exposed to a second processing solution that is less acidic than the first, thus minimizing the exposure of the bone body to the harsh acidic conditions of the demineralization phase of the process.