George Eisenbarth,Li Zhang,John Kappler,Brian Stadinski
申请号:
US13376122
公开号:
US20120171212A1
申请日:
2010.06.03
申请国别(地区):
US
年份:
2012
代理人:
摘要:
The present invention is directed to therapeutic compositions and methods for the prevention or treatment of autoimmune diseases, comprising molecules that disrupt or prevent the assembly of the trimolecular complex required for the T cell immune response comprising the autoantigen, the MHC class II molecule, and the T cell receptor implicated in the autoimmune disease.