KISHIMOTO, TAKASHI KEI,FRASER, CHRISTOPHER,MALDONADO, ROBERTO A.
申请号:
CA2834534
公开号:
CA2834534A1
申请日:
2012.04.27
申请国别(地区):
CA
年份:
2012
代理人:
摘要:
Disclosed are synthetic nanocarrier methods, and related compositions, comprising administering MHC Class I-restricted and/or MHC Class II-restricted epitopes of an antigen and immunosuppressants in order to generate tolerogenic immune responses against the antigen, such as the generation of antigen- specific CD8+ regulatory T cells.