A left atrial appendage occluder includes a sealing plate, a fixing plate, and a connection member connecting the sealing plate and the fixing plate. The connection member is a silk woven structure. A radial deformability of the sealing plate is greater than a radial deformability of the fixing plate, and/or an axial deformability of the sealing plate is greater than an axial deformability of the fixing plate. In the left atrial appendage occluder, the fixing plate and the sealing plate are connected via the connection member of the silk woven structure, such that a distance between the fixing plate and the sealing plate and an angle formed thereby are both adjustable to adapt to a left atrial appendage having a large bending angle or requiring the fixing plate to remain at an increased distance to the sealing plate, thereby reducing the risk of failed occlusion.
