使用PD-1軸結合拮抗劑和抗GPC3抗體治療癌症的方法

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专利权人:

CHUGAI SEIYAKU KABUSHIKI KAISHA;GENENTECH, INC.

发明人:

ENDO, MIKA,远藤美香,遠藤美香,KATO, ATSUHIKO,加藤淳彦,OHTOMO, TOSHIHIKO,大友俊彦,ADACHI, KENJI,足立健児,KINOSHITA, YASUKO,木下恭子,NARITA, YOSHINORI,成田义规,成田義規

申请号：

TW106108296

公开号：

TW201740975A

申请日:

2017.03.14

申请国别(地区):

TW

年份:

2017

代理人:

摘要：

The invention provides compositions and methods for treating cancers. The methods comprising administering a PD-1 axis binding antagonist and an anti-GPC3 antibody. The compositions comprising a pharmaceutical composition for treating cancer which comprises a PD-1 axis binding antagonist and an anti-GPC3 antibody. Also disclosed are a pharmaceutical composition to be used in combination with a PD-1 axis binding antagonist for treating cancer which comprises an anti-GPC3 antibody as the active ingredient； and a pharmaceutical composition to be used in combination with an anti-GPC3 antibody for treating cancer which comprises as the active ingredient a PD-1 axis binding antagonist.本發明提供用於治療癌症的組成物及方法。所述方法包含施用PD-1軸結合拮抗劑及抗GPC3抗體。所述組合物包含用於治療癌症的醫藥組成物，其包含PD-1軸結合拮抗劑及抗GPC3抗體。亦揭示與PD-1軸結合拮抗劑組合使用於治療癌症的醫藥組成物，其包含抗GPC3抗體作為活性成分；以及與抗GPC3抗體組合使用於治療癌症的醫藥組成物，其包含PD-1軸結合拮抗劑作為活性成分。

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/