The dry yeast composition which is superior in the S adenoshiru L methionine of this invention and the retention stability which contains the thickener is offered. Because retention stability, furthermore the dry yeast which includes the S adenoshiru L methionine which is superior in organism absorptivity in high density can be produced simply and economically the yeast which possesses SAMe productivity after adding the thickener to the yeast fungus body concentrate which the culture collection germ is done by drying, the useful S adenoshiru L methionine is included in high density as a water soluble bioactive substance, retention stability, furthermore the dry yeast composition which is superior in organism absorptivity can be offered to the market.本発明のS-アデノシル-L-メチオニンと、増粘剤を含有する保存安定性に優れた乾燥酵母組成物を提供する。SAMe生産能を有する酵母を培養集菌した酵母菌体濃縮物に増粘剤を添加した後に乾燥することによって、保存安定性、さらには生体吸収性に優れたS-アデノシル-L-メチオニンを高濃度に含む乾燥酵母を簡便かつ経済的に製造できるので、水溶性の生理活性物質として有用なS-アデノシル-L-メチオニンを高濃度に含む、保存安定性、さらには生体吸収性に優れた乾燥酵母組成物を市場に提供できる。