PROBLEM TO BE SOLVED: To provide fluorine-containing carboxylic acid derivatives useful as, e.g., active ingredients of pharmaceuticals for prevention and/or treatment of various pains such as chronic pain including neuropathic pain.SOLUTION: The invention provides fluorine-containing carboxylic acid derivatives represented by the general formula (I), or salts thereof or esters thereof. (R1 is a C1-5 alkyl group substituted by at least one fluorine atom, e.g., a 2-fluoroethyl group, a 2,2-difluoroethyl group, or the like and R2 and R3 are each independently H, an alkyl group, an alkenyl group, or an acyl group.)COPYRIGHT: (C)2015,JPO&INPIT【課題】種々の神経因性疼痛を含む慢性疼痛などの疼痛の予防及び/又は治療のための医薬の有効成分などに有用なフッ素含有カルボン酸誘導体の提供。【解決手段】一般式(I)で表されるフッ素含有カルボン酸誘導体、又はその塩若しくはそのエステル。(R1は少なくとも1個のフッ素原子で置換されたC1~5個のアルキル基(例えば2-フルオロエチル基、2,2-ジフルオロエチル基等);R2及びR3は各々独立にH、アルキル基、アルケニル基、又はアシル基)【選択図】なし
