NICOUD, IAN B.,CLARKE, DOMINIC M.,MATTHEW, ABY J.,RICE, MICHAEL
申请号：
CA2719825
公开号：
CA2719825C
申请日:
2009.03.27
申请国别(地区):
CA
年份:
2018
代理人:
摘要：
The present invention relates to materials and methods for hypothermiccollection of whole blood, and componentsthereof, which can extend the holding time of blood beyond the current useablelimit. Additionally, blood can be drawn directlyinto a hypothermic preservation solution without the addition of standardanticoagulants. This is enabled by providing sustainedcellular viability under hypothermic conditions using a nutrient matrix devoidof animal proteins and containing energy substrates,free-radical scavengers, and impermeants that is ionically balanced forstorage of biologic materials at low temperatures to preventcellular stress-induced apoptosis.
