The present application provides T cells comprising an antigen and an adjuvant, methods of manufacturing such T cells, and methods of using such T cells, such as for modulating an immune response in an individual.本申請案提供包含抗原及佐劑之T細胞、製造該T細胞之方法及使用該T細胞以諸如調節個體之免疫反應之方法。