Mohammad Tadayyon;Roland Maier;Michael Mark;Ralf Lotz;Elke Langkopf;Frank Himmelsbach;Matthias Eckhardt
发明人:
Frank Himmelsbach,Elke Langkopf,Matthias Eckhardt,Michael Mark,Roland Maier,Ralf Lotz,Mohammad Tadayyon
申请号:
US12143128
公开号:
US08178541B2
申请日:
2008.06.20
申请国别(地区):
US
年份:
2012
代理人:
摘要:
The present invention relates to substituted xanthines of general formulawherein R1 to R3 are as defined herein, the tautomers, the stereoisomers, the mixtures, the prodrugs thereof and the salts thereof which have valuable pharmacological properties, particularly an inhibiting effect on the activity of the enzyme dipeptidylpeptidase-IV (DPP-IV).