Roland MAIER;Michael MARK;Ralf R.H. LOTZ;Elke LANGKOPF;Frank HIMMELSBACH;Matthias ECKHARDT
发明人:
Frank HIMMELSBACH,Michael MARK,Matthias ECKHARDT,Elke LANGKOPF,Roland MAIER,Ralf R.H. LOTZ
申请号：
US13523938
公开号：
US20120252782A1
申请日:
2012.06.15
申请国别(地区):
US
年份:
2012
代理人:
摘要：
The present invention relates to substituted xanthines of general formulawherein R1 to R4 are defined as in claim 1, the tautomers and the stereoisomers thereof, mixtures thereof, the prodrugs and the salts thereof which have valuable pharmacological properties, particularly an inhibiting effect on the activity of the enzyme dipeptidylpeptidase-IV (DPP-IV).
