MARK, MICHAEL,MARK, Michael,HIMMELSBACH, FRANK,HIMMELSBACH, Frank,LANGKOPF, ELKE,LANGKOPF, Elke,ECKHARDT, MATTHIAS,ECKHARDT, Matthias,MAIER, ROLAND,MAIER, Roland,LOTZ, RALF, R., H.,LOTZ, Ralf, R., H.
申请号：
RSP13912
公开号：
RS20120139A2
申请日:
2003.08.18
申请国别(地区):
RS
年份:
2012
代理人:
摘要：
Invention herewith described refers to the 8-[3-amino-piperidin-1-yl]-xanthines, the production thereof and the use of the same as medicaments i.e. to the substituted xanthines of the general formula (I) whereat R1 to R3 are defined as in the requirements 1 to 16, to their tautomers, stereoisomers, mixtures, their pro-drugs and their salts that have valuable pharmaceutical properties, particularly an inhibitory effect on the activity of dipeptidyl peptidase - IV (DPP-IV) enzyme.Predmetni pronazak se odnosi na supstituisane ksantine opšte formule pri čemu su R1 do R3 definisani kao u zahtevima 1 do 16, na njihove tautomere, stereoizomere, smeše, njihove prolekove i njihove soli koje imaju vredna farmaceutska svojstva, a posebno inhibirajuće dejstvo na aktivnost enzima dipeptidilpeptidaze - IV (DPP-IV).
