Michael J. KELLY, III;Rajan ANAND;Ronald M. KIM;Deping WANG;Tianying JIAN;Thomas J. GRESHOCK;Anthony J. ROECKER;Gang;Liangqin GUO;Philippe NANTERMET;Ting ZHANG;Walter WON;James MULHEARN;Mark E. LAYTON
发明人:
Thomas J. Greshock,James Mulhearn,Liangqin Guo,Ting Zhang,Deping Wang,Ronald M. Kim,Mark E. Layton,Michael J. Kelly, III,Rajan Anand,Philippe Nantermet,Tianying Jian,Anthony J. Roecker,Walter Won,Gang
申请号：
US16061815
公开号：
US20180362518A1
申请日:
2016.12.15
申请国别(地区):
US
年份:
2018
代理人:
摘要：
Disclosed are compounds of Formula A, or a salt thereof, where Q, X, R1 and R2 are as defined herein, which compounds have properties for inhibiting Na 1.7 ion channels found in peripheral and sympathetic neurons. Also described are pharmaceutical formulations comprising the compounds of Formula A or their salts, and methods of treating pain (acute, post-operative, neuropathic), or cough or itch disorders using the same.
