The present invention relates spiro-cyclic amine derivatives of the formula (I)whereinR1 is selected fromcyano,(2-4C)alkenyl, (2-4C)alkynyl, (1-4C)alkyl each optionally substituted with CN or one or more fluoro atoms,(3-6C)cycloalkyl, (4-6C)cycloalkenyl or a (8-10C)bicyclic group, each optionally substituted with halogen or (1-4C)alkyl,phenyl, biphenyl, naphthyl, each optionally substituted with one or more substituents independently selected from halogen, cyano, (1-6C)alkyl optionally substituted with one or more fluoro atoms, (1-6C)alkoxy optionally substituted with one or more fluoro atoms, amino, di(1-4C)alkylamino and (3-6C)cycloalkyl optionally substituted with phenyl which may be substituted with (1-4C)alkyl or halogen,phenyl substituted with phenoxy, benzyl, benzyloxy, phenylethyl or monocyclic heterocycle, each optionally substituted with (1-4C)alkyl optionally substituted with one or more fluoro atoms,monocyclic heterocycle optionally independently substituted with halogen, (1-6C)alkyl optionally substituted with one or more fluoro atoms, (3-6C)cycloalkyl, or phenyl optionally substituted with (1-4C)alkyl or halogen,andbicyclic heterocycle optionally substituted with halogen or (1-4C)alkyl optionally substituted with one or more fluoro atoms；-Y-(Cn-alkylene)-X- is a linking group whereinY is attached to R1 and selected from a bond, -O-, -CO-, -S-, -SO-, -SO2-, -NH-, -CH=CH-, -C(CF3)=CH-, -C≡C-, -CH2-O-, -O-CO-, -CO-O-, -CO-NH-, -NH-CO-, and trans-cyclopropylene；n is an integer from 0 to 10； andX is attached to the phenylene/pyridyl moiety and selected from a bond, -O-, -S-, -SO-, -SO2-, -NH-, -CO-, -CH=CH-, and trans-cyclopropylene；R2 is H or independently selected from one or more substituents selected from halogen, (1-4C)alkoxy and (1-4C)alkyl optionally substituted with one or more fluor atoms； andR3 is (1-4C)alkylene-R4 wherein the alkylene group may be substituted with one or more halogen atoms or with (CH2)2 to form
