PROBLEM TO BE SOLVED: To provide a novel peptide that is efficient as vaccine for a cancer highly expressing P-cadherin (CDH3) such as pancreatic cancer, cholangiocellular carcinoma, stomach cancer, colorectal cancer and lung cancer, and to provide a medicinal agent for therapy and prophylaxis of the cancer including the peptide.SOLUTION: A peptide having a specified amino acid sequence, or the peptide, in the amino acid sequence of the peptide, comprising an amino acid sequence in which one or several amino acids are substituted, deleted, inserted and/or added and having inducible activity of cytotoxic (killer) T-cell is provided.【課題】膵癌、胆管細胞癌、胃癌、大腸癌、肺癌など、P-cadherin(CDH3)を高発現する癌に対するワクチンとして有効な新規ペプチド、及び当該ペプチドを含む癌の治療および予防のための薬剤を提供する。【解決手段】特定のアミノ酸配列を有するペプチド、もしくは前記ペプチドのアミノ酸配列において、1個または数個のアミノ酸が置換、欠失、挿入、及び/又は付加されたアミノ酸配列からなるペプチドであって、細胞傷害性(キラー)T細胞の誘導活性を有するペプチド。【選択図】なし