As for this invention, the new displacement benzo thiazole derivative and displacement benzookisazoru derivative, with medicine constituent, and DPP 1 which include these those uses in remedying of the disease and the condition which the modulate are done are designated as purpose.本発明は、新しい置換ベンゾチアゾール誘導体及び置換ベンゾオキサゾール誘導体、これらを含む薬剤組成物、並びにDPP-1によってモジュレートされる疾患及び病状の治療におけるそれらの使用を目的とする。