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BONE IMPLANT
专利权人:
Ecole Polytechnique Fédérale de Lausanne (EPFL), Lausanne, CH;Université de Genève, Geneve, CH;Université de Genève; Geneve; CH
发明人:
DESCOUTS, Pierre, F-74160 Neydans, FR,ARONSSON, Björn-Owe, CH-1255 Veyrier, CH,GRÄTZEL, Michael, CH-1025 St. Sulpice, CH,VIORNERY, Carine, F-29660 Carantec, FR,PECHY, Peter, CH-1012 Lausanne, CH
申请号:
DE60121361
公开号:
DE000060121361T3
申请日:
2001.11.19
申请国别(地区):
DE
年份:
2012
代理人:
摘要:
Compounds having phosphonic acid groups or a derivative thereof, corresponding to the general formula (I) €ƒ€ƒ€ƒ€ƒ€ƒ€ƒ€ƒ€ƒ A-[P(O)(OH) 2 ] p €ƒ€ƒ€ƒ€ƒ€ƒ(I), or a pharmaceutically acceptable derivative thereof, wherein A means a residue of a linear, branched or cyclic, saturated or unsaturated, hydrocarbon residue with n carbon atoms, whereby said residue may be substituted by hydroxyl and/or carboxyl and optionally further interrupted by one or more oxygen and/or sulphur and/or nitrogen atoms, carrying p phosphonic acid groups, wherein n is a number from 4 to 70, and p is 3, 4, 5 or 6, are especially suitable to treat surfaces of Endosseous implants to be applied to a human or animal bone to improve osseointegration.
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