Methods and compositions for generating an immune response by inducing CD40 and pattern recognition receptor adapters

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专利权人:

发明人:

David Spencer,Priyadharshini Narayanan

申请号：

US15216008

公开号：

US09976122B2

申请日:

2016.07.21

申请国别(地区):

US

年份:

2018

代理人:

摘要：

Provided are methods for activating an antigen-presenting cell and eliciting an immune response by inducing an inducible pattern recognition receptor adapter, or adapter fragment, and CD40 activity. Also provided are nucleic acid compositions comprising sequences coding for chimeric proteins that include an inducible CD40 peptide and an inducible pattern recognition receptor adapter or adapter fragment.

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