WEEDEN TIMOTHY E,NELSON CAROL A,WENTWORTH BRUCE M,CLAYTON NICHOLAS P,LEGER ANDREW
申请号:
IN201637043337
公开号:
IN201637043337A
申请日:
2016.12.19
申请国别(地区):
IN
年份:
2017
代理人:
摘要:
The present disclosure relates to antisense oligonucleotides (AONs) such as phosphorodiamidate morpholino oligonucleotides (PMOs). The present disclosure further relates to the conjugation of multiple PMOs to cationic cell penetrating peptides (CPPs) to enhance the uptake of PMOs into skeletal and cardiac muscle cells.