WEEDEN, TIMOTHY E.,NELSON, CAROL A.,WENTWORTH, BRUCE M.,CLAYTON, NICHOLAS P.,LEGER, ANDREW
申请号:
SG11201608880V
公开号:
SG11201608880VA
申请日:
2015.05.22
申请国别(地区):
SG
年份:
2016
代理人:
摘要:
The present disclosure relates to antisense oligonucleotides (AONs), such as phosphorodiamidate morpholino oligonucleotides (PMOs). The present disclosure further relates to the conjugation of multiple PMOs to cationic cell penetrating peptides (CPPs) to enhance the uptake of PMOs into skeletal and cardiac muscle cells.