Dhan Sidhartha Chand,Nicholas Stuart Wilson,Dennis John Underwood
申请号：
US15968094
公开号：
US20180355040A1
申请日:
2018.05.01
申请国别(地区):
US
年份:
2018
代理人:
摘要：
The instant disclosure provides antibodies that specifically bind to T-cell immunoreceptor with Ig and ITIM domains (TIGIT) (e.g., human TIGIT) and antagonize TIGIT function. Also provided are pharmaceutical compositions comprising these antibodies, nucleic acids encoding these antibodies, expression vectors and host cells for making these antibodies, and methods of treating a subject using these antibodies.
