Chand, Dhan Sidhartha,Wilson, Nicholas Stuart,Underwood, Dennis John,Morin, Benjamin Maxime
申请号：
AU2018263857
公开号：
AU2018263857A1
申请日:
2018.05.01
申请国别(地区):
AU
年份:
2019
代理人:
摘要：
The instant disclosure provides antibodies that specifically bind to T-cell immunoreceptor with Ig and ITIM domains (TIGIT) (e.g., human TIGIT) and antagonize TIGIT function. Also provided are pharmaceutical compositions comprising these antibodies, nucleic acids encoding these antibodies, expression vectors and host cells for making these antibodies, and methods of treating a subject using these antibodies.
