用於治療成癮的作為乙醛脫氫酶-2抑制劑的N-[4-(2-氧基-1，2-二氫-吡啶-4-基)-芐基]-苯甲酰胺衍生物

• 收藏
• 分享

专利权人:

Gilead Sciences Inc.

发明人:

CANNIZZARO, Carina, E.,GRAUPE, Michael,GUERRERO, Juan, A.,LU, Yafan,STICKLEY, Robert, G.,VENKATARAMANI, Chandrasekar,ZABLOCKI, Jeff

申请号：

HK16105461.1

公开号：

HK1217487A

申请日:

2016.05.12

申请国别(地区):

HK

年份:

2017

代理人:

摘要：

Disclosed are N-[4-(2-oxo-1,2-dihydro-pyridin-4-yl)-benzyl]-benzamide derivatives which are useful as human mitochondrial aldehyde dehydrogenase (ALDH-2) inhibitors for treating chemical dependency on dopamine-producing agents such as cocaine, opiates, amphetamines, nicotine and alcohol. Also disclosed are pharmaceutical compositions comprising a therapeutically effective amount of said compounds and methods of using the compounds in the treatment of addiction.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/