COMBINATION CANCER IMMUNOTHERAPY WITH PENTAAZA MACROCYCLIC RING COMPLEX

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专利权人:

GALERA LABS; LLC

发明人:

BEARDSLEY, Robert A.,KEENE, Jeffery L.,RILEY, DENNIS P.

申请号：

SG11201909495P

公开号：

SG11201909495PA

申请日:

2018.04.13

申请国别(地区):

SG

年份:

2019

代理人:

摘要：

wI) ---G:GC4419(1)1anti-PD1 RMP1-1415 ---4---GIGC4419(10) G5:GC4419(3)lanii-PD1 RMP1 1415 RMP1-14(5) —13--MGC4419(10)/anti-PD1 RMP -1 5) 1500 20 40 Days Post Tumor Implantation FIG. 1 W O 20 18/ 19 167 6 Al (12) INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY (PCT) (19) World Intellectual Property Organization International Bureau (43) International Publication Date 18 October 2018 (18.10.2018) W I PO I PCT omit VIII °nolo mu Oil 1001111 IIII iflo oimIE (10) International Publication Number WO 2018/191676 Al (51) International Patent Classification: A61K 33/32 (2006.01) A61K 39/395 (2006.01) A61K 39/00 (2006.01) A61P 35/00 (2006.01) (21) International Application Number: PCT/US2018/027588 (22) International Filing Date: 13 April 2018 (13.04.2018) (25) Filing Language: English (26) Publication Language: English (30) Priority Data: 62/485,061 13 April 2017 (13.04.2017) US 62/572,377 13 October 2017 (13.10.2017) US (71) Applicant: GALERA LABS, LLC [US/US]； 1100 Corpo- rate Square Drive, Suite 223, Creve Coeur, Missouri 63132 (US). (72) Inventors: BEARDSLEY, Robert A.； 6935 Waterman Ave, University City, Missouri 63130 (US). KEENE, Jef- fery L.； 8100 Leafland Court, St. Louis, Missouri 63123 (US). RILEY, Dennia P.； 1722 Claymont Estates Drive, Chesterfield, Missouri 63107 (US). (74) Agent: COTTON, Abigail； c/o Bryan Cave LLP, 211 North Broadway, Suite 3600, St. Louis, Missouri 63102 (US). (81) Designated States (unless otherwise indicated, for every kind of national protection available): AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC

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