DERIVES DE 1-(HET)ARYLSULFONYLE- (PYRROLIDINE OU PIPERIDINE)-2-CARBOXAMIDE ET LEUR UTILISATION COMME ANTAGONISTES DE TRPA1

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专利权人:

F. HOFFMANN-LA ROCHE AG

发明人:

ESTRADA, ANTHONY,VOLGRAF, MATTHEW,CHEN, HUIFEN,KOLESNIKOV, ALEKSANDR,VILLEMURE, ELISIA,VERMA, VISHAL,WANG, LAN,SHORE, DANIEL,DO, STEVEN,YUEN, PO-WAI,HU, BAIHUA,WU, GUOSHENG,LIN, XINGYU,LU, AIJUN

申请号：

CA2975196

公开号：

CA2975196A1

申请日:

2016.02.12

申请国别(地区):

CA

年份:

2016

代理人:

摘要：

The invention is concerned with the compounds of formula I and salts thereof and other compounds of formulas II-IX as disclosed herein. In addition, the present invention relates to methods of manufacturing and methods of using the compounds of formulas I-IX as well as pharmaceutical compositions containing such compounds. The compounds may be useful in treating diseases and conditions mediated by TRPA1, such as pain or asthma.

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中国工程科技知识中心

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http://www.ckcest.cn/home/