PROBLEM TO BE SOLVED: To provide a manufacturing method of medical equipment which can easily form a polymer coating, exhibits excellent wettability and has high water resistance.SOLUTION: The medical equipment is manufactured by an arrangement step A1, a preparation step A2 and a coating formation step A3. In the arrangement step A1, a substrate is arranged. In the preparation step A2, a first polymer having a phosphorylcholine group and a second polymer having a phosphorylcholine group and hydrophilicity different from that of the first polymer are dissolved in an organic solvent to prepare the polymer mixed solution. In the coating formation step A3, a substrate is impregnated into the polymer mixed solution and then dried to form a hydrophilic coating including the first polymer and the second polymer in at least a part of surface of the substrate.SELECTED DRAWING: Figure 1COPYRIGHT: (C)2018,JPO&INPIT【課題】 容易に高分子皮膜を形成することができ、濡れ性に優れ、高い耐水性を有する医療機器の製造方法を提供する。【解決手段】 工程A1の準備工程で、基材を準備し、工程A2の調製工程で、ホスホリルコリン基を有する第1重合体および第1重合体と親水性が異なる、ホスホリルコリン基を有する第2重合体を有機溶媒に溶解させて重合体混合溶液を調製する。工程A3の皮膜形成工程で、重合体混合溶液に基材を浸漬させたのち乾燥させて、基材の少なくとも一部の表面に第1重合体および第2重合体を含む親水性皮膜を形成することで、医療機器を製造する。【選択図】 図1
