Daniel D. Long;Daisuke Roland Saito;John R. Jacobsen
发明人:
Daisuke Roland Saito,Daniel D. Long,John R. Jacobsen
申请号：
US13031873
公开号：
US08268863B2
申请日:
2011.02.22
申请国别(地区):
US
年份:
2012
代理人:
摘要：
The invention provides novel 8-azabicyclo[3.2.1]octane compounds of formula (I):where the variables are defined in the specification, or a pharmaceutically-acceptable salt thereof, that are antagonists at the mu opioid receptor. The invention also provides pharmaceutical compositions comprising such compounds, methods of using such compounds to treat conditions associated with mu opioid receptor activity, and processes and intermediates useful for preparing such compounds.
