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Intravascular indwelling catheter lock solution containing weak acid and container containing the same
专利权人:
Yuko Kimura
发明人:
Yuko Kimura,Koji Suzuki,Minoru Iwata,Sumika Iwamoto,Takashi Yamamoto
申请号:
US13133123
公开号:
US08703739B2
申请日:
2008.12.05
申请国别(地区):
US
年份:
2014
代理人:
摘要:
A catheter lock solution which is a catheter lock preparation having a bacteriostatic property at physiological osmotic pressure without practically containing a bacteriostatic component such as a preservative, an antimicrobial agent, or an antibiotic and having high safety, characterized in that the preparation contains a weak acid having an acid dissociation constant (pKa) of 3.0 to 6.5 as a buffer, a pH of the solution is less than 6.0, preferably from 3.0 to about 5.5, an osmotic pressure ratio is from 0.5 to 3.0, and a pH change (variation) can be suppressed to less than the 6.0 with the weak acid, and a container containing the catheter lock solution.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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