William McGHEE,Michelle SCHMIDT,Margaret GRAPPERHAUS,Kah Tiong KUAN
申请号：
US16348433
公开号：
US20200079785A1
申请日:
2017.11.08
申请国别(地区):
US
年份:
2020
代理人:
摘要：
The present invention provides MMC prodrug compounds and liposomal MMC prodrugs and compositions thereof for the treatment of cancer. The compositions include liposomes containing a phosphatidylcholine lipid, a sterol, a PEG-lipid and a MMC prodrug. The present invention also provides liposomal compositions for the treatment of cancer comprising administering to a patient in need thereof a liposome, wherein the liposome comprises: a phosphatidylcholine lipid； a sterol； a PEG-lipid and a MMC prodrug or a pharmaceutically-acceptable salt thereof.
