Generally, a dry-wet grain fractionation system which provides a dry mill process (26) for the production of grain fractions (14) (15) (16) and a wet mill process (18) for the production of purified bran (19), endosperm (20) and germ (21) from the mixture of grain particles in a grain fraction (14) (15) or (16) or combinations thereof. Specifically, a dry-wet grain fractionation system for production of corn germ (21) having increased protein and oil content and an endosperm (20) having increased starch and sugar content.