FIEBIG, HELMUT,NANDY, ANDREAS,CROMWELL, OLIVER,FIEBIG HELMUT,NANDY ANDREAS,CROMWELL OLIVER
申请号:
PL04803420
公开号:
PL1709064T3
申请日:
2004.12.01
申请国别(地区):
PL
年份:
2012
代理人:
摘要:
The present invention relates to the provision of a DNA sequence of the major grass pollen allergen Lol p 4. The invention also encompasses fragments, new combinations of partial sequences and point mutants having a hypoallergenic action. The recombinant DNA molecules and the derived polypeptides, fragments, new combinations of partial sequences and variants can be utilized for the therapy of pollen-allergic diseases. The proteins prepared by recombinant methods can be employed for in vitro and in vivo diagnosis of pollen allergies.