Helmut Fiebig,Andreas Nandy,Roland Suck,Oliver Cromwell,Arnd Petersen,Wolf-Meinhard Becker
申请号：
US10518927
公开号：
US08128935B2
申请日:
2003.06.11
申请国别(地区):
US
年份:
2012
代理人:
摘要：
The present invention relates to the provision of the genetic sequence of the major grass pollen allergen Phl p 4. The invention also covers fragments, new combinations of partial sequences and point mutants having a hypoallergenic action. The recombinant DNA molecules and the derived polypeptides, fragments, new combinations of partial sequences and variants can be utilised for the therapy of pollen-allergic diseases. The proteins prepared by recombinant methods can be employed for the in vitro and in vivo diagnosis of pollen allergies.
