A suturing device for use with a tubular vessel, tissue or organ including a hollow housing, an activation mechanism and a flexible suture guide. The suturing device includes a suture which may be pre-knotted or include a crimp, anchor or other retaining means. The flexible suture guide of the suturing device is placed around the outer diameter of the tubular vessel, tissue or organ and the activation mechanism causes the suture to be placed around the outer diameter of the tubular vessel, tissue or organ and knotted. The suturing device may include a severing means which severs the suture at the knot.
