Koikov, Leonid;University Of Cincinnati;Knittel, James J.;Abdel-Malek, Zalfa A.
发明人:
申请号：
EP13856556.9
公开号：
EP2922565B1
申请日:
2013.11.20
申请国别(地区):
EP
年份:
2019
代理人:
摘要：
Short tri- and tetrapeptides according to the following Formula I Ar(CH2)mX1—X2—CO—X3—X4—X5-(Trp)n-NX6R are potent, selective agonists of melanocortin 1 receptor (MC1R). Provided herein are skin care compositions including Formula I peptide agonists of MC1R and methods of regulating a skin condition of a mammal that include applying to a treatment surface of the body a safe and effective amount of a skin care composition including a Formula I peptide. The peptides, skin care compositions, and skin care methods described herein are useful in regulating a skin condition of a mammal associated with exposure ultraviolet (UV) radiation, including sunburn, UV sensitivity, photoaging, and skin pigmentation, particularly in the absence of sun exposure.
