ABDEL-MALEK, ZALFA A.,KOIKOV, LEONID,KNITTEL, JAMES J.
申请号：
CA2892134
公开号：
CA2892134A1
申请日:
2013.11.20
申请国别(地区):
CA
年份:
2014
代理人:
摘要：
Short tri- and tetrapeptides according to the following Formula I Ar(CH2) m X1-X2-CO-X3-X4-X5-(Trp) n -NX6R are potent, selective agonists of melanocortin 1 receptor (MC1R). Provided herein are skin care compositions including Formula I peptide agonists of MC1R and methods of regulating a skin condition of a mammal that include applying to a treatment surface of the body a safe and effective amount of a skin care composition including a Formula I peptide. The peptides, skin care compositions, and skin care methods described herein are useful in regulating a skin condition of a mammal associated with exposure ultraviolet (UV) radiation, including sunburn, UV sensitivity, photoaging, and skin pigmentation, particularly in the absence of sun exposure.
