KERSCHBAUMER, RANDOLF,SCHEIFLINGER, FRIEDRICH,RIEGER, MANFRED,THIELE, MICHAEL,MUDDE, C
申请号:
NZ59640908
公开号:
NZ596409A
申请日:
2008.12.30
申请国别(地区):
NZ
年份:
2013
代理人:
摘要:
NZ 596409 Disclosed is a monoclonal antibody or an antigen-binding portion thereof that specifically binds to the C-terminal region of macrophage migration inhibitory factor (MIF) and inhibits human MIF biological function, wherein the C-terminal region is the region spanning amino acids 86 to 102 of human MIF. The disclosed antibodies are used in the manufacture of a medicament for treating an immunological disease in a subject.