<;P>;PROBLEM TO BE SOLVED: To provide a macrophage migration inhibition factor (MIF) antisecretory agent. <;P>;SOLUTION: The macrophage migration inhibition factor antisecretory agent contains daisy fleabane or its extract. Preferably, the extract of daisy fleabane is an ethanolic extract or a water extract. <;P>;COPYRIGHT: (C)2009,JPO&INPIT