進階糖化終產物（ＡＧＥ）前驅物之螯合劑农业专利-农业学术服务平台

发明人:: HOLMES-FARLEY, S. RANDALL,福尔摩斯法利　斯兰德尔,福爾摩斯法利　斯蘭德爾,DHAL, PRADEEP,德哈尔　派达帕,德哈爾　派達帕,BESEV, MAGNUS,贝斯　马格努斯,貝斯　馬格努斯,MILLER, ROBERT J.,米勒　罗伯特,米勒　羅伯特,福尔摩斯法利斯兰德尔,福爾摩斯法利斯蘭德爾,德哈尔派达帕,德哈爾派達帕,贝斯马格努斯,貝斯馬格努斯,米勒罗伯特,米勒羅伯特

摘要：: Sequestrants of AGE precursors comprise amines separated by 2, 3 or 4 carbons. Sequestrants of AGE precursors can be used as pharmaceutical agents and in pharmaceutical compositions. The sequestrants of AGE precursors are particularly useful binding AGE precursors and dietary dicarbonyls in mammals in the gastrointestinal tract for the treatment of ailments such as diabetic nephropathy, chronic renal disease, atherosclerosis, stroke, cataracts, and Alzheimer’s disease.AGE前驅物之螯合劑包括被2、3或4個碳分開之胺。AGE前驅物之螯合劑可用作醫藥劑及用於醫藥組成物中。AGE前驅物之螯合劑特別可用於結合AGE前驅物和哺乳動物胃腸道中膳食二羰基，供治療疾病例如糖尿病腎病變、慢性腎疾病、動脈硬化、中風、白內障和阿茲海默症。