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SEQUESTRANTS OF ADVANCED GLYCATION END PRODUCT (AGE) PRECURSORS
专利权人:
GENZYME CORPORATION
发明人:
Stephen Randall Holmes-Farley,Pradeep K. Dhal,Magnus Besev,Robert J. Miller,Andrew T. Papoulis
申请号:
US15842177
公开号:
US20180265613A1
申请日:
2017.12.14
申请国别(地区):
US
年份:
2018
代理人:
摘要:
Sequestrants of AGE precursors comprise amines separated by 2, 3 or 4 carbons. Sequestrants of AGE precursors can be used as pharmaceutical agents and in pharmaceutical compositions. The sequestrants of AGE precursors are particularly useful binding AGE precursors and dietary dicarbonyls in mammals in the gastrointestinal tract for the treatment of ailments such as diabetic nephropathy, chronic renal disease, atherosclerosis, stroke, cataracts, and Alzheimer's disease.
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