DHAL, Pradeep,MILLER, Robert, J.,HOLMES-FARLEY, Stephen, Randall,BESEV, Magnus
申请号:
TN2015000390
公开号:
TN2015000390A1
申请日:
2015.09.04
申请国别(地区):
TN
年份:
2017
代理人:
摘要:
Sequestrants of AGE precursors comprise amines separated by 2, 3 or 4 carbons. Sequestrants of AGE precursors can be used as pharmaceutical agents and in pharmaceutical compositions. The sequestrants of AGE precursors are particularly useful binding AGE precursors and dietary dicarbonyls in mammals in the gastrointestinal tract for the treatment of ailments such as diabetic nephropathy, chronic renal disease, atherosclerosis, stroke, cataracts, and Alzheimer's disease.