DOUNAY AMY BETH,HELAL CHRISTOPHER JOHN,TUTTLE JAMISON BRYCE,VERHOEST PATRICK ROBERT
申请号:
IN4320/DELNP/2013
公开号:
IN2013DN04320A
申请日:
2013.05.14
申请国别(地区):
IN
年份:
2014
代理人:
摘要:
The present invention relates to compounds 3 amino 1 hydroxy 2 oxo 1 2 3 4 tetrahydroquinoline 7 carbonitrile 3 amino 1 hydroxy 7 (2 methoxyethoxy) 3 4 dihydroquinolin 2(1H) one and 3 amino 1 hydroxy 7 [(1S) 2 methoxy 1 methylethoxy] 3 4 dihydroquinolin 2(1H) one including racemic mixtures and resolved enantiomers thereof to pharmaceutically acceptable salts thereof and to the treatment of cognitive deficits associated with schizophrenia and other psychiatric neurodegenerative and/or neurological disorders in mammals including humans.