DOUNAY, AMY BETH,HELAL, CHRISTOPHER JOHN,TUTTLE, JAMISON BRYCE,VERHOEST, PATRICK ROBERT
申请号：
SG2013036314
公开号：
SG190246A1
申请日:
2011.11.18
申请国别(地区):
SG
年份:
2013
代理人:
摘要：
The present invention relates to compounds 3-amino-1-hydroxy-2- oxo-1,2,3,4-tetrahydroquinoline-7-carbonitrile, 3-amino-1-hydroxy-7-(2- methoxyethoxy)-3,4-dihydroquinolin-2(1H)-one, and 3-amino-1-hydroxy-7-[(1S)-2-methoxy-1-methylethoxy]-3,4-dihydroquinolin-2(1H)-one, including racemic mixtures and resolved enantiomers thereof, to pharmaceutically acceptable salts thereof, and to the treatment of cognitive deficits associated with schizophrenia and other psychiatric, neurodegenerative and/or neurological disorders in mammals, including humans.
