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ROTIGOTINE-CONTAINING PATCH
专利权人:
HISAMITSU PHARMACEUTICAL CO.; INC.
发明人:
Hiroyuki ARAKI,Yuka TAKAGI,Yoko FUJIWARA,Hiroaki KOBAYASHI,Takao KUROKAWA
申请号:
US16954627
公开号:
US20200306203A1
申请日:
2018.12.14
申请国别(地区):
US
年份:
2020
代理人:
摘要:
The present invention provides a rotigotine-containing patch comprising: a backing layer; and an adhesive agent layer, wherein the adhesive agent layer contains rotigotine and/or a pharmaceutically acceptable salt thereof,the adhesive agent layer further contains a styrene-based thermoplastic elastomer, a petroleum-based resin and/or a terpene-based resin, an aliphatic alcohol, and a cross-linked polyvinylpyrrolidone, andin the adhesive agent layer, a mass ratio of a content of the rotigotine and/or the pharmaceutically acceptable salt thereof in terms of rotigotine free form and a content of the cross-linked polyvinylpyrrolidone (content of the rotigotine and/or the pharmaceutically acceptable salt thereof in terms of rotigotine free form:content of the cross-linked polyvinylpyrrolidone) is 10:3 to 1:3.
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