Kovtun, Yelena,Tavares, Daniel,Rui, Lingyun,Chittenden, Thomas
申请号:
AU2016285552
公开号:
AU2016285552A1
申请日:
2016.06.28
申请国别(地区):
AU
年份:
2018
代理人:
摘要:
The present disclosure generally relates to antibodies, antigen-binding fragments thereof, polypeptides, and immunoconjugates that bind to CD 123 antigen (the a chain of the interleukine 3 receptor, or IL-3Ra). The present disclosure also relates to methods of using such CD123-binding molecules for diagnosing and treating diseases, such as B-cell malignancies.