Yelena Kovtun,Daniel J. Tavares,Lingyun Rui,Thomas Chittenden
申请号:
US15957757
公开号:
US20180355047A1
申请日:
2018.04.19
申请国别(地区):
US
年份:
2018
代理人:
摘要:
The present invention generally relates to antibodies, antigen-binding fragments thereof, polypeptides, and immunoconjugates that bind to CD123 antigen (the a chain of the interleukine 3 receptor, or IL-3Rα). The present invention also relates to methods of using such CD123-binding molecules for diagnosing and treating diseases, such as B-cell malignancies.