Anti-CD123 antibodies and conjugates and derivatives thereof

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专利权人:

ImmunoGen; Inc.

发明人:

Yelena Kovtun,Daniel Tavares,Lingyun Rui,Thomas Chittenden

申请号：

US15195401

公开号：

US10077313B2

申请日:

2016.06.28

申请国别(地区):

US

年份:

2018

代理人:

摘要：

The present invention generally relates to antibodies, antigen-binding fragments thereof, polypeptides, and immunoconjugates that bind to CD123 antigen (the α chain of the interleukine 3 receptor, or IL-3Rα). The present invention also relates to methods of using such CD123-binding molecules for diagnosing and treating diseases, such as B-cell malignancies.

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