DETECTION METHOD OF SERTRALINE IN BLOOD PLASMA

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专利权人:

KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY

发明人:

JUNG, BONG CHEOL,JUNG, BYEONG HWA,KIM, GYEONG MI

申请号：

KR20020018083

公开号：

KR20030079218(A)

申请日:

2002.04.02

申请国别(地区):

韩国

年份:

2003

代理人:

摘要：

PURPOSE: A detection method of sertraline in blood plasma is provided, thereby rapidly and accurately detecting sertraline in blood plasma. CONSTITUTION: A detection method of sertraline in blood plasma comprises the steps of: removing proteins from animal blood plasma; regulating pH of the protein-removed blood plasma to 11.5 to 12.5; extracting the pH-regulated blood plasma with a nonpolar solvent; and measuring the concentration of the extracted sertraline using gas chromatography/mass spectrometer, wherein the nonpolar solvent is diethylether; and the pH regulation is carried out by using Na2HPO4-NaOH.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/