CLAUDE A. QUESNELLE,HAIQUAN FANG,MIKKEL V. DEBENEDETTO,ANDREW P. DEGNAN,JOHN E. STARRETT JR.,WEN HAN,ASHVINIKUMAR V. CHING - GAVAI,DEREK J. NORRIS,GEORGE V. DELUCCA,HONG HUANG,PATRICE GILL,DANIEL OMAL
申请号：
ARP140104912
公开号：
AR099379A1
申请日:
2014.12.23
申请国别(地区):
AR
年份:
2016
代理人:
摘要：
3. Tricyclohexyltin compounds, pharmaceutical acceptable ingredients containing current compounds, and methods of using these ingredients to treat various disorders. Claim 1: a compound with formula characteristics, the characteristics of which are: A is an optional heteromorphic substitute or an optional heteromorphic substitute, and the substitute is one or more R； R is one or more hydrogen, halogen, halide, hydroxyl compound, cn.cf.83323；CH F CHFC₁₋₆ optionally substituted alkyl, C₁₋₆ optionally substituted alkoxy, C₃₋₆ optionally substituted cycloalkyl, optionally substituted heterocycle, -OR⁴,-CONR³R⁴,-R83088；NR³R⁴C₁₋₆ alquil-,-No. 8310；-NR⁶COR³,NR⁶COR³C₁₋₆ rent,-No. 8310； No. co8322； No. 3,NR⁶CO₂R³C₁₋₆ alquil-,-8310； - r83088；-SO NR RSO₂C₁₋₆ alquil-,-No. 8310； - No. so8322； - No. r83088；-NR⁶SO₂R⁴ o NR⁶SO₂R⁴C₁₋₆ alquil-；X and Y are independently selected from hydrogen, C₁₋₆ optionally substituted alkyl, C₃₋₈ optionally substituted cycloalkyl, optionally substituted aryl, optionally substituted heteroaryl or optionally substituted heterocycle； Z is hydrogen, halogen, -OH, C₁₋₆ alkyl, C₁₋₆ alkoxy, -NR³R⁴,-CONR³R⁴,-OCONR³R⁴,-No. 8310；-8310； - r83088；-NR⁶SO₂NR³R⁴ o -NR⁶SO₂R⁴；R1 is one or more hydrogen, halogen, - CN, - or8308；-R83088；-CONR³R⁴,-COOH, -OCONR³R⁴,-No. 8310；-8310； - r83088；-No. 8310； - No. so8322； - No. r83088；-No. 8310； - No. 18322； - No. 830808；C₁₋₆ optionally substituted alkyl, C₂₋₆ optionally substituted alkenyl, C₂₋₆ optionally substituted alkynyl, C₁₋₆ optionally substituted alkoxy, C₃₋₈ optionally substituted cycloalkyl, C₃₋₈ optionally substituted cycloalkyl-C₁₋₆ optionally substituted cycloalkyl-CO, optionally substituted C₃₋₈ cycloalkyl-SO₂, optionally substituted aryl-C₁₋₆, optionally substituted C₃₋₈ cycloalkyl-C₁₋₆, optionally substituted heterocyclyl-CO, optionally substituted heterocyclyl, C₁ ₋₆ alkyl-SO₂- optionally substituted,C₁₋₆ alkyl-NR⁶SO⁶- optionally substituted, heterocycle-NR⁶SO₂- optionally substituted, C₁₋₆ alkyl-NR⁶SO₂- optio
