Barry Smith,Carlos Cordon-Cardo,Daniel Petrylak,Josep Domenech,Mireia Castilla Martin
申请号：
US14005058
公开号：
US20140364402A1
申请日:
2012.03.22
申请国别(地区):
US
年份:
2014
代理人:
摘要：
The present invention provides, inter alia, a method for identifying an agent that selectively decreases the number of cancer stem cells (CSCs). This method includes (a) contacting a CSC from a population of cells with a candidate agent and (b) determining whether the candidate agent reduces the survival or growth of the CSC or increases differentiation of the CSC relative to a CSC that has not been contacted with the candidate agent. The method may be used as a high throughput screen.
